Firma #10 Weight Loss Pill
Delivered every 23 days. Cancel anytime.
$125.00
every 23 days
$125.00
$399.00
one-time purchase
About This Product
What's Included
- ✓ Firma #10 Capsule — Topiramate 15mg / Bupropion 65mg / Naltrexone 8mg / Methylcobalamin-B12 1mg / Phentermine 10mg
- ✓ Telehealth Access
30-day supply (30 capsules) per order.
Procedure
Take one extended-release capsule by mouth once daily, with or without food. Swallow whole — do not crush or chew. Instructional materials provided after purchase.
Purpose
Firma #10 is a comprehensive, multi-mechanism weight loss capsule combining four clinically studied active ingredients into a single daily slow-release dose. Rather than targeting one pathway, it simultaneously addresses appetite suppression, reward-driven eating, and metabolic regulation — with Methylcobalamin-B12 added for energy and neurological support throughout your weight loss journey.
Dosing Schedule
Once daily — taken at the same time each day, with or without food.
Diet and Exercise
Healthy eating and activity are recommended for best results.
Benefits
- Weight Loss
- Reduced appetite and food cravings
- May improve Blood Pressure
- May improve Cholesterol
- Improved energy and neurological support (Methylcobalamin-B12)
Most Common Side Effects
Side effects vary by ingredient. The most commonly reported include dry mouth, insomnia, headache, constipation, and nausea. These are typically mild and tend to diminish with continued use.
Recommendations to limit Nausea: Eat bland, low-fat foods, like crackers, toast, and rice. Eat foods that contain water, like soup and gelatin. Avoid laying down after eating. Eat slowly. Go outdoors for fresh air.
Physician Consent for Treatment: A physician may contact you within 24 hours of purchase if additional information is needed.
Important
This product contains Bupropion and Naltrexone. Do not take if you have a history of seizures, eating disorders (anorexia or bulimia), or are currently taking MAOIs. Do not take Naltrexone if you are currently using opioids or opioid-containing medications. Inform your physician of all current medications before starting.
Shipping
This product does not require refrigeration and can be shipped standard, 2-Day, or Overnight. Store at room temperature away from heat and moisture.
The Science Behind Firma #10
Firma #10 combines two clinically validated drug pairings — Topiramate/Phentermine and Naltrexone/Bupropion — into one convenient daily capsule, alongside Methylcobalamin-B12 for metabolic and neurological support. Each ingredient targets a distinct mechanism, delivering a synergistic, multi-pathway approach to weight management.
Phentermine + Topiramate
Phentermine is a sympathomimetic amine that suppresses appetite by stimulating the release of norepinephrine in the hypothalamus. Topiramate is an anticonvulsant that further reduces appetite and increases satiety through multiple CNS mechanisms including GABA receptor modulation and carbonic anhydrase inhibition. Together, this combination is one of the most effective pharmacological interventions for obesity. In clinical trials, the branded combination (Qsymia) produced average weight loss of approximately 10% of body weight at one year — among the highest of any approved weight loss medication.
Naltrexone + Bupropion
Bupropion is a dopamine and norepinephrine reuptake inhibitor that activates pro-opiomelanocortin (POMC) neurons in the hypothalamus, reducing appetite. Naltrexone is an opioid receptor antagonist that blocks a natural feedback loop that would otherwise blunt Bupropion's appetite-suppressing effects — allowing the combination to work more powerfully together than either agent alone. This pairing (the mechanism underlying Contrave) has been shown in clinical trials to produce significantly greater weight loss than placebo, alongside improvements in cardiometabolic markers.
Methylcobalamin-B12
Methylcobalamin is the active, neurologically bioavailable form of Vitamin B12. It supports mitochondrial energy production, neurological function, and red blood cell formation. During caloric restriction and weight loss, B12 status can decline; supplementation helps maintain energy levels and supports the neurological pathways that regulate metabolism and mood throughout the weight loss process.
References
This compounded medication is a customized formulation prepared for individual patients in accordance with Section 503A of the Federal Food, Drug, and Cosmetic Act, dispensed solely pursuant to a valid patient-specific prescription from a licensed healthcare provider.
The individual active ingredients in this formulation (Topiramate, Phentermine, Bupropion, and Naltrexone) are FDA-approved drugs. This specific combined compounded formulation has not been independently evaluated or approved by the FDA. It is not affiliated with or intended to replace any branded combination product.
This medication is not made for resale, bulk distribution, or office use, and is compounded exclusively to meet the clinical needs of individual patients when commercially available alternatives are not appropriate.